Monday, November 2, 2015  12:00 – 1:30 pm, in 489 Minor Hall

Graduate Student Seminar

presented by

 Adeloa Harewood, PhD Candidate (Michael Silver’s Lab)

and

Stella Kang, PhD Candidate (Lu Chen’s Lab)

 

Speaker: Adeloa Harewood, PhD Candidate (Silver Lab)

Title: Visual field shape and critical spacing in visual crowding

Abstract: Behavioral performance is better in the lower than in the upper visual field for a variety of perceptual tasks, including visual crowding. We recently showed that the lower visual field advantage for visual crowding could be accounted for by asymmetry in the shape of the visual field along the vertical meridian. Here, we are continuing this work by studying visual field asymmetries in critical spacing – the minimum distance between a target and its flankers that is needed to enable a certain level of performance on a crowding task. Upper and lower visual field extents were measured in each participant with a Goldmann perimeter. Participants then completed a crowding task in which they discriminated the orientation of a target grating in the presence of flanker gratings. The target grating was always on the vertical meridian, in either the upper or lower visual field. We found smaller critical spacing in the lower visual field than in the upper visual field when stimuli were placed at the same eccentricity, consistent with a lower visual field advantage. However, when stimulus locations were matched based on percentage of visual field extent instead of visual angle, critical spacing was similar in the upper and lower visual fields.

Speaker: Stella Kang (Lu Chen’s Lab)

Title: Intravital imaging reveals dynamics of corneal lymphangiogenesis

Lymphatic research signifies a field of rapid progression in recent years. Though lymphatic dysfunction has been found in a myriad of disorders, to date, few effective treatments are available for lymphatic diseases. It is therefore urgent to develop new experimental approaches and therapeutic protocols. The cornea offers an ideal site for lymphatic research due to its transparent nature, accessible location, and lymphatic-free but –inducible features. In this study, taking advantage of the live imaging system we recently developed, we are able to reveal the multifaceted dynamics of corneal lymphangiogenesis from the initiation to regression phases. Further investigation holds the great potential for divulging new mechanisms and therapeutic strategies for lymphatic diseases occurring both inside and outside the eye.

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