|AFFILIATIONS||Assistant Professor of Clinical Optometry and Vision Science|
|RESEARCH||The emphasis of my research has been on the investigation of optical influences on emmetropization and the development of myopia. Using chicken as a model, I have identified a number of optical designs that significantly inhibit myopia progression, thus have potential translational value in controlling human myopia. Additionally, I have been designing and fitting contact lenses to young guinea pig cornea to evaluate the safety, feasibility and effectiveness of contact lenses as a method of inducing defocus for myopia research in mammalian models.|
Y Zhang, Y Liu, C Ho, CF Wildsoet. Effects of imposed defocus of opposite sign on temporal gene expression patterns of BMP4 and BMP7 in chick RPE. Experimental Eye Research (2013), Apr; 109:98–106. Paper.
Liu and C.F. Wildsoet. The effective add inherent in 2-zone negative lenses inhibits eye growth in young chicks. IOVS 2012, Jul;53(8):5085-93
Zhang, Y Liu, and C.F. Wildsoet. Bidirectional, Optical Sign-Dependent Regulation of BMP2 Gene Expression in Chick Retinal Pigment Epithelium. IOVS 2012, Sep; 53(10): 6072-80
Ostrin, Y Liu, V Choh, and C.F. Wildsoet. The role of iris in chick accommodation. IOVS 2011, Jun; 52(7) 4710-16
Liu and C.F. Wildsoet. The effect of 2-zone concentric bifocal spectacle lenses on refractive error development and eye growth in young chicks. IOVS 2011 Feb 22;52(2):1078-865.
Vedamurthy, WW Harrison, Y Liu, I Cox, and CM Schor. The influence of first near-spectacle reading correction on accommodation and its interaction with convergence. IOVS. 2009, Sep;50(9):4215-22