New Imaging Breakthrough from Roorda Lab
By Liza Shevchuk
Congratulations to Vision Science PhD student Jason Wong and Postdoctoral Scholar Shangbang (Jacob) Luo, co-first authors on a new paper published in Biomedical Optics Express! Their research, conducted in Dr. Austin Roorda’s lab and supported by the National Eye Institute, showcases a groundbreaking imaging technique that combines adaptive optics scanning laser ophthalmoscopy (AOSLO) and adaptive optics optical coherence tomography (AOOCT) to perform optoretinography (ORG) in the human eye.
What makes this system unique is its ability to use real-time eye tracking to lock onto a single cone photoreceptor and measure its ORG response — offering greater temporal resolution than any system to date for measuring cone activity. Even more exciting, this technique may one day enable researchers to detect tiny, rapid physical changes in other retinal neurons; perhaps even ganglion cell action potentials.
This is an exciting step forward in high-resolution functional imaging, and also Jason's first, first-author paper! Congratulations again to Jason, Jacob, and the full research team!
Photo courtesy of Jason Wong and Jacob Luo: OCT image of a small patch of cones.