Oxyopia Abstract

February 15, 2008
Friday, 4:00 PM
489 Minor Hall

Brad Fortune, OD, PhD
Associate Scientist, Discoveries in Sight Research Laboratories, Devers Eye Institute, Portland
Host: Robert Greer

Faculty Search Candidate

Title

Bench to Bedside: Diagnostic Methods for Glaucoma Research and Clinical Care

Abstract

Numerous experimental models of glaucoma exist for studying disease pathogenesis and avenues for potential therapeutic intervention. However the endpoints commonly used in the large clinical trials and other studies of human patients (e.g., visual field status measured by standard automated perimetry) are rarely suitable for studies on laboratory animals. This lecture will present alternative measures of vision function based on various modes of electroretinography, as well as some of the relatively new techniques for retinal nerve fiber layer assessment, which can all be used as outcome measures in experimental animal models of glaucoma and in clinical studies in glaucoma patients. Emphasis will be placed on relative strengths, weaknesses and limitations of each technique, though emerging insights about glaucoma pathogenesis will also be presented.

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